1/4/2023 0 Comments Peter sykes pdfPost-menopausal bleeding (PMB) represents an absolute indication for specialist gynaecological investigation because of the underlying risk of endometrial cancer, estimated at 10%.1 The aim of clinical management of PMB is to achieve an accurate diagnosis without over-investigation.In recent years, newer methods of investigation of PMB, such as transvaginal ultrasonography (TVUS), endometrial biopsy, and hysteroscopy, have superseded dilation and curettage (D&C).2 Most guidelines3-7 use an endometrial thickness (ET) of 55mm measured by TVUS to indicate an increased risk of endometrial cancer in post-menopausal women, with conservative management recommended for those with an ET 8mm.Despite numerous studies comparing the effectiveness, safety and acceptability of methods for investigating PMB and detecting malignant pathology, there is still no consensus on the most accurate and efficient diagnostic clinical pathway.
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